Preparative LC systems

Dynamic Axial Compression Columns DAD

YMC provides dynamic axial compression columns (DAC) suited for various separation scales such as laboratory-, pilot- and industrial-scale. They are automated self packing columns that allow for an easy, cost-effective refill of packing material that results in a column bed yielding superior durability and reproducibility. DAD series which can be operated easy unpacking with downward cylinder driving direction, DAU series which are compact design with upward cylinder driving direction, and rotatable custom-designed DAR series are available.

* DAU and DAR are special orders.

POINT
  • Cost-effective provided by self-packing
  • Superior column performance, durability and reproducibility provided by constant pressurization (Axial Compression Technology)
  • Optional slurry container permits hygiene automated packing procedures
  • High performance packing provided by simple and safety operation
  • Compatible with IQ/OQ and explosion-proof operation

Features

Prevention of voids by constant pressurization

In packing operation of axially compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenous packed bed. Packed bed pressurized by cylinder realizes high performance columns which are high densely and homogenously packed. Prevention of voids by constant pressurization also realizes long column life as a result of improvement of durability. (Axial Compression Technology)

Optional slurry container permits automated packing procedures

The slurry container provides excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

Column performance

The data on the right hand side shows repacking data obtained by using a 50 mmI.D. DAC column. After 7 times repacking, plates/m and Tf are still as good as the initial state.

Seamless scale-up

The chromatography on the right hand side are a scale-up example from an analytical 4.6 mmI.D. column to a 50 mmI.D. DAC column. This indicates that the very similar separation pattern of analytical scale is also reproducible at the preparative scale.

Seamless scale-up