Columns
YMC-Triart C18 ExRS is a high-coverage C18 phase based on organic/inorganic hybrid silica particles. The hydrophobicity of YMC-Triart C18 ExRS is high due to the high carbon loading (25%), which makes YMC-Triart C18 ExRS suitable for use with hydrophobic isomers and structural analogs. Given the superior chemical and physical durability of YMC-Triart C18 ExRS, chromatographers are afforded additional flexibility in choosing separation conditions for both method development and routine column usage.
| SPECIFICATION | |
| Base | organic/inorganic hybrid silica |
|---|---|
| Particle size | 1.9 µm, 3 µm, 5 µm |
| Pore size | 80 Å |
| Carbon content | 25% |
| pH range | 1-12 |
| USP class | L1 |
A mixture that consists of compounds with various characteristics is analyzed with Triart C18 and Triart C18 ExRS. Triart C18 ExRS has lower polarity and higher hydrophobicity than the standard Triart C18 column, and also shows improved shape recognition.
1. Amitriptyline (basic compound)
2. 8-Quinolinol (coordination compound)
3. Testosterone (polar compound)
4. Naphthalene (π-π interaction)
5. Ibuprofen (acidic compound)
6. Propylbenzene (hydrophobicity)
7. n-Butylbenzene (hydrophobicity)
8. o-Terphenyl (planar cognitive ability)
9. Triphenylene (planar cognitive ability)
| Column | 5 μm, 150 X 3.0 mmI.D. |
|---|---|
| Eluent | 20 mM KH2PO4-H3PO4 (pH 3.1)/methanol (25/75) |
| Flow rate | 0.425 mL/min |
| Temperature | 40°C |
| Detection | UV at 265 nm |
| Injection | 4 µL |
Triart ExRS is effective for separating structural analogs. This feature is especially useful for separating pharmaceuticals with structurally similar impurities.
Vitamin D2 and Vitamin D3
| Column | 5 µm, 150 X 3.0 mmI.D. |
|---|---|
| Eluent | THF/acetonitrile (10/90) |
| Flow rate | 0.425 mL/min |
| Temperature | 30°C |
| Detection | UV at 265 nm |
| Injection | 4.25 µL (10 µg/mL) |
